Current Issue
VOL. 2 / NO. 2
Reflections on genetic and epigenetic impacts of industrial chemical exposure in workers
César J. D'Pool Fernández
Occupational toxicologist at the Ecuadorian 'Populorum Progressio' Fund (FEPP), Codesarrollo Bank and Recamier Laboratory. Professor at the Central University of Ecuador (UCE) and the Ibero-American University of Ecuador (UNIB.E).
Submitted: 2025-06-11
Accepted: 2025-06-20
Published: 2025-06-30
DOI: 10.62129/IDGM3617
Article PDF
Abstract
Genetic and epigenetic effects resulting from industrial chemical exposure significantly impact worker health. Exosomes play a critical role in mediating intercellular communication, while the exposome concept provides a comprehensive framework for understanding cumulative environmental and lifestyle influences. Cellular adaptations through allostasis illustrate the dynamic response to toxic stress, underscoring the necessity for integrated risk assessment that considers environmental and socioeconomic variables.
Keywords Exosomes Exposome Epigenetics Occupational exposure Chemical toxicity
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